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Klinefelter syndrome (ks), also known as 47,xxy, is a chromosome anomaly where a male has an extra x chromosome It results from meiotic nondisjunction occurring during gametogenesis of the egg or sperm with subsequent fertilization of an xx ovum by a y bearing sperm, or fertilization of an x ovum by a sperm. [10] the complications commonly including infertility and small, poorly functioning testicles (if present).

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47,xxy (klinefelter syndrome) is a chromosomal variation in males where one extra x chromosome is present which then results in a 47,xxy 31 apparently, the prenatal incidence may be even higher, but abortive loss may be as high as 90% during the first trimester. The extra x chromosome typically affects physical, neurodevelopmental, behavioral and neurocognitive functioning.

Klinefelter syndrome, also called 47,xxy, is a chromosomal condition that affects male development

The signs and symptoms of klinefelter syndrome vary In some cases, the features are so mild that the condition is not diagnosed until puberty or adulthood Researchers believe that up to 65 percent of people with klinefelter syndrome are never diagnosed A karyotype of 47,xxy may also be expected as mosaic with a 46,xy but the present case is rarely reported

There have been studies reporting the low risk of malignancy in patients with the ovotesticular disorders. Longer cag repeats in androgen receptor gene correlate with severity. 47,xxy, commonly known as klinefelter syndrome, is a chromosomal condition that affects male development This genetic variation is characterized by the presence of an extra x chromosome in males, resulting in a 47,xxy karyotype instead of the typical 46,xy.

Presence of the xx cell line ranged from 5% to 98% in patient specimens.