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Any mutant allele can be classified into one of five types Changes in the dna base pair sequence of the hypomorphic allele may cause one or more of the following, with the gene still. (1) amorph, (2) hypomorph, (3) hypermorph, (4) neomorph, and (5) antimorph

Glossomics: Leaky Mutation

Other articles where leaky mutation is discussed These alleles are sometimes referred to as leaky mutations, because they provide some function, but not complete, normal function For the minute gene, we concluded that the organism needs both copies to have a wild type phenotype

Loss of one copy (an amorphic mutation) produces a dominant visible mutant phenotype

Deletion of the gene is an example of a classic amorphic mutation These alleles are sometimes referred to as leaky mutations. Mutations in body cells (somatic mutations) cannot do this but can cause cloned abnormalities including cancers See also frame shift mutation, insertion mutation, inversion mutation, leaky mutation, lethal mutation, missense mutation, point mutation, nonsense mutation.

A leaky mutation is a type of mutation that partially impairs a certain characteristic or function in the mutant, rather than eliminating it completely For instance, normal auxotrophic mutants don´t grow at all in the lack of the appropriate medium However, it is common to find some leaky mutants that grow very slowly in the absence of the appropriate supplements. This usually leads to the production of an inactive protein

Single base additions or deletions lead to frameshift.